Awesome Privacy

Incredibly powerful, network-wide ad-blocker. Works out-of-the-box, light-weight with an intuitive web interface, but still allows for a lot of advanced configuration for power users. As well as blocking ads and trackers, Pi-Hole speeds up your network speeds quite significantly. The dashboard has detailed statistics, and makes it easy to pause/ resume Pi-Hole if needed.

Native Apple (Swift) apps, for system-wide ad-blocking. Can be customized with custom host lists, primarily aimed for just ad-blocking.

A POSIX-compliant shell script, designed for Unix-like systems, that gets a list of domains that serve ads, tracking scripts and malware from multiple sources and creates a hosts file (alternative formats are also supported) that prevents your system from connecting to them. Aimed at improving security and privacy through blocking advert, tracking and malware associated domains.

Open source mobile ad-blocker that acts like a firewall. Since it's device-wide, once connected all apps will have ads/ trackers blocked, and the blacklist can be edited. The app is free, but there is a premium option, which has a built-in VPN.

Free and open source ad-blocker and a firewall for Android 6+ (no root required).

Python script that uses machine learning to block adverts in live audio streams, such as Radio, Podcasts, Audio Books, and music platforms such as Spotify. See live demo.

Light-weight, fast browser extension for Firefox and Chromium (Chrome, Edge, Brave Opera etc), that blocks tracking, ads and known malware. uBlock is easy-to-use out-of-the-box, but also has a highly customisable advanced mode, with a point-and-click firewall which can be configured on a per-site basis.